Predictors of contrast-induced nephropathy in ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention

Abstract Background Contrast-induced nephropathy (CIN) is a serious complication with primary percutaneous coronary intervention (PPCI). We aimed to study the different predictors of CIN and determine cutoff point contrast volume (CV)/creatinine clearance (CrCl) applicability CHA2DS2-VASC score in prediction after PPCI ST-elevation myocardial infarction (STEMI) patients. Four hundred patients presented STEMI eligible for PCI were included study. Patients GFR < 30 ml/min excluded from Results Fifty-four (13.5%) who developed older (64.20 ± 13.16 vs. 55.80 10.58) had higher prevalence diabetes mellitus (DM), hypertension (HTN), female gender than those without CIN. They also Killip class lower hemoglobin (HB) level ( P 0.05) compared no The incidence was (85.8%) low-risk Mehran group 14.2% moderate-risk group, all high very <0.001). Multiple logistic regression showed that old age (OR= 1.06, 95% CI= 1.02–1.11, 0.001), sex 3.1, 2.65–6.99, = 0.02), (OR=2.48, 1.98–6.24, 0.01), CV/CrCl > 2.8 (odds ratio=1.45, 1.22–2.01, 0.03), 2 ratio=1.90, 1.76–2.11, P= 0.04) Conclusions Old age, sex, score, CHADS2-VASC 2, underwent PPCI.